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| https://www.sciencenews.org/sites/default/files/18295 (This is not the research of Emory University researchers.) |
Are you a big eater? Well a study shows that eating more
many not simply be because of all the calories that are ready and available.
This study suggests that microbes in the gut could actually help drive
appetite. Sounds crazy right? Well, let’s get right into this new study by
Emory University researchers.
Previous studies show that overweight people and
normal-weight people each carry different types and amounts of microbes that
naturally live in the intestine. The Emory University researchers looked into
mice to see why this was and found shocking information. The mice with an
altered immune system were fatter than regular mice and had many disorders such
as insulin problems and high blood pressure.
The altered “immunity” in the mice mean “somewhat” different bacteria
grew in their intestines than that in normal mice. According to Andrew Gewirtz who is an
associate pathology professor at Emory, this drove bigger appetites, metabolic
syndrome, and a low-grade inflammation believed to be key to obesity’s
illnesses.
Gewirtz then transferred bacteria from the fat mice into the
germ-free intestines of normal newborn mice. These “newborn” mice than began
eating more and developed inflammation and insulin problems like the “fat
mice.” Gewirtz also noted that if you restrict access to food, the altered mice
do not gain weight, but experience other symptoms.
This article was very interesting due to the fact that
microbes have such a huge impact on us. In class I learned that microbes
actually help digest food but to hear they can also be causing you to eat more
is pretty fascinating! I believe this article was well written but I feel it
should have included more detail; such as what actual microbe or microbes were causing
more mice to eat. Are these the same microbes found in mice that are found in
humans? I feel this article should have included more “human research” if there
is any. Overall this article was shocking and makes you realize all the things
microbes can do to your body.
http://www.latimes.com/health/sns-health-bacteria-big-eaters,0,1246678.story#axzz2uwFwnRyf

Hi, I am a PhD student in Dr. Northup's lab. Interesting article. The question I would ask is if some people with a "normal" body weight also have a microbial flora similar to obese individuals and this makes it more likely that they will get obese. I am not sure of the sample size of the study to know if this could be the case. Or if peoples gut flora changes as they become obese.
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